Discussion 3: Immunosuppression
Discussion 3: Immunosuppression
A 34-year-old Hispanic-American male with end-stage renal
disease received kidney transplant from a cadaver donor, as no
one in his family was a good match. His post-operative course was
uneventful, and he was discharged with the antirejection drugs
Tacrolimus (Prograf), Cyclosporine (Neoral), and Imuran
(Azathioprine). He did well for 3 months and had returned to his
job as a policeman. Six months after his transplant, he began to
gain weight, had decreased urine output, was very fatigued, and
began to run temperatures up to 101˚F. He was evaluated by his
nephrologist, who diagnosed acute kidney transplant rejection.
Develop a 1- to 2-page case study analysis, examining the patient
symptoms presented in the case study. Be sure to address the
following:
Explain why you think the patient presented the symptoms
described.
The response includes accurate, clear, and detailed reasons, with
explanation for the symptoms supported by evidence and/or
research, as appropriate, to support the explanation.
Identify the genes that may be associated with the development
of the disease.
The response includes an accurate, complete, detailed, and
specific analysis of the genes that may be associated with the
development of the disease

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