Question

Week 1 quiz

Question 1. The major impact of the physiological changes that occur with aging is:

Reduced physiological reserve

Reduced homeostatic mechanisms

Impaired immunological response

All of the above

Question 2. Men have faster and more efficient biotransformation of drugs and this is thought to be due to:

Less obesity rates than women

Prostate enlargement

Testosterone

Less estrogen than women

Question 3. The cytochrome p system involves enzymes that are generally:

Inhibited by drugs

Induced by drugs

Inhibited or induced by drugs

Associated with decreased liver perfusion

Question 4. Functional abilities are best assessed by:

Self-report of function

Observed assessment of function

A comprehensive head-to-toe examination

Family report of function

Question 5. Iron Deficiency Anemia (IDA) is classified as a microcytic, hypochromic anemia. This classification refers to which of the following laboratory data?

Hemoglobin and Hematocrit

Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH)

Serum ferritin and serum iron

Total iron binding capacity and transferrin saturation

Question 6. When interpreting laboratory data, you would expect to see the following in a patient with Anemia of Chronic Disease (ACD):

Hemoglobin <12 g/dl, MCV decreased, MCH decreased

Hemoglobin >12 g/dl, MCV increased, MCH increased

Hemoglobin <12 g/dl, MCV normal, MCH normal

Hemoglobin >12 g/dl, MCV decreased, MCH increased

Question 7. The pathophysiological hallmark of ACD is:

Depleted iron stores

Impaired ability to use iron stores

Chronic unable bleeding

Reduced intestinal absorption of iron

Question 8. The main focus of treatment of patients with ACD is:

Replenishing iron stores

Providing for adequate nutrition high in iron

Management of the underlying disorder

Administration of monthly vitamin B12 injections

Question 9. In addition to the complete blood count (CBC) with differential, which of the following laboratory tests is considered to be most useful in diagnosing ACD and IDA?

Serum iron

Total iron binding capacity

Transferrin saturation

Serum ferritin

Question 10. Symptoms in the initial human immunodeficiency virus (HIV) infection include all of the following except:

Sore throat

Fever

Weight loss

Headache

Question 11. Essential parts of a health history include all of the following except:

Chief complaint

History of the present illness

Current vital signs

All of the above are essential history components

Question 12.Which of the following clinical reasoning tools is defined as evidence-based resource based on mathematical modeling to express the likelihood of a condition in select situations, settings, and/or patients?

Clinical practice guideline

Clinical decision rule

Clinical algorithm

Clinical recommendation

Question 13. The first step in the genomic assessment of a patient is obtaining information regarding:

Family history

Environmental exposures

Lifestyle and behaviors

Current medications

Question 14.In autosomal recessive (AR) disorders, individuals need:

Only one mutated gene on the sex chromosomes to acquire the disease

Only one mutated gene to acquire the disease

Two mutated genes to acquire the disease

Two mutated genes to become carriers

Question 15. In AR disorders, carriers have:

Two mutated genes; two from one parent that cause disease

A mutation on a sex chromosome that causes a disease

A single gene mutation that causes the disease

One copy of a gene mutation but not the disease

Question 16. A woman with an X-linked dominant disorder will:

Not be affected by the disorder herself

Transmit the disorder to 50% of her offspring (male or female)

Not transmit the disorder to her daughters

Transmit the disorder to only her daughters

Question 17. According to the Genetic Information Nondiscrimination Act (GINA):

Nurse Practitioners (NPs) should keep all genetic information of patients confidential

NPs must obtain informed consent prior to genetic testing of all patients

Employers cannot inquire about an employee’s genetic information

All of the above

Question 18. Which of the following would be considered a “red flag” that requires more investigation in a patient assessment?

Colon cancer in family member at age 70

Breast cancer in family member at age 75

Myocardial infarction in family member at age 35

All of the above

Question 19. Your 2-year-old patient shows facial features, such as epicanthal folds, up-slanted palpebral fissures, single transverse palmar crease, and a low nasal bridge. These are referred to as:

Variable expressivity related to inherited disease

Dysmorphic features related to genetic disease

De novo mutations of genetic disease

Different penetrant signs of genetic disease

Question 20.In order to provide a comprehensive genetic history of a patient, the NP should:

Ask patients to complete a family history worksheet

Seek out pathology reports related to the patient’s disorder

Interview family members regarding genetic disorders

All of the above