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Posted: July 30th, 2023

Anorexia Nervosa: Understanding the Neurology, Implications, and Evidence-Based Treatment

Explain the neurology of this eating or feeding disorder (Anorexia Nervosa). Does the characterization of this eating or feeding disorder as a mental illness surprise you? What are your thoughts on the personal and/or cultural implications of classifying an eating or feeding disorder in this way, as opposed to a lifestyle choice or a matter of willpower? How might you support a family (or client) who is resistant to this seeing an eating or feeding disorder as a mental illness?
Describe changes in personality and social behavior that might be seen with this eating or feeding disorder. How would you assess for these changes?
Provide an overview of the health consequences and medical complications of this eating or feeding disorder.
Create a treatment plan for an individual diagnosed with this eating or feeding disorder using family-based therapy or other evidence-based therapy.

Answer these questions succinctly, integrating resources to provide rationale for all decisions.
You may use narrative, bullets, or a table format for various sections of this discussion assignment.
Use at least one reference from CINAHL

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Anorexia Nervosa: Understanding the Neurology, Implications, and Evidence-Based Treatment

Introduction:
Anorexia Nervosa (AN) is an eating disorder characterized by a persistent restriction of food intake, resulting in significantly low body weight, fear of gaining weight, and a distorted perception of body image. This academic article aims to delve into the neurology of AN, discuss its classification as a mental illness, explore the personal and cultural implications of such classification, examine changes in personality and social behavior, and outline a treatment plan utilizing family-based therapy and evidence-based approaches.

Neurology of Anorexia Nervosa:
AN is associated with various neurobiological factors, contributing to its complex etiology. Neuroimaging studies have revealed alterations in brain structures involved in appetite regulation, emotional processing, and cognitive control. Aberrations in the hypothalamus, insula, amygdala, and prefrontal cortex have been observed, indicating disruptions in the regulation of hunger, satiety, and emotional responses.
Furthermore, neurotransmitter imbalances, particularly involving serotonin and dopamine systems, are implicated in AN. These neurochemical alterations may influence mood, anxiety, and reward processing, reinforcing disordered eating behaviors. Genetic factors also play a role, as evidenced by familial clustering of AN cases and identified genetic risk variants associated with the disorder.

Classification as a Mental Illness:
The characterization of AN as a mental illness aligns with the current understanding of its multifactorial nature and the significant impact on an individual's psychological well-being. Despite the role of societal and cultural factors in shaping body image ideals, AN is not merely a lifestyle choice or a matter of willpower. It is essential to recognize the neurological and psychological underpinnings, acknowledging that individuals suffering from AN require specialized mental health interventions.

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Personal and Cultural Implications:
Classifying AN as a mental illness rather than a lifestyle choice helps reduce stigma and promote access to appropriate healthcare services. By acknowledging the complex neurobiology involved, we can foster empathy and understanding towards individuals battling AN. However, cultural factors may influence how AN is perceived and addressed, leading to variations in treatment-seeking behaviors and recovery outcomes.

Supporting Resistant Families/Clients:
Supporting families or clients resistant to acknowledging AN as a mental illness requires a compassionate and empathetic approach. It is essential to provide evidence-based information, emphasizing the medical and psychological consequences of AN. Utilizing motivational interviewing techniques and involving family members in the treatment process can facilitate acceptance and engagement in therapy.

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Changes in Personality and Social Behavior:
AN can lead to significant changes in personality and social behavior. Common features include social withdrawal, irritability, anxiety, and a heightened need for control. Individuals with AN may exhibit perfectionism and exhibit increased sensitivity to perceived criticism, leading to strained interpersonal relationships.

Assessment of Personality and Social Changes:
To assess for changes in personality and social behavior, clinicians may utilize standardized psychological assessments, such as the Minnesota Multiphasic Personality Inventory (MMPI) and the Beck Depression Inventory (BDI). Additionally, conducting interviews with family members and close friends can provide valuable insights into the individual's behavioral changes.

Health Consequences and Medical Complications:
AN can result in severe health consequences and medical complications, including electrolyte imbalances, cardiovascular issues, gastrointestinal disturbances, bone density loss, and hormonal abnormalities. Left untreated, these complications can lead to long-term health problems and increased mortality risk.

Treatment Plan: Family-Based Therapy (FBT) and Evidence-Based Approaches:
A comprehensive treatment plan for AN should incorporate family-based therapy (FBT) as the primary intervention, especially for adolescents. FBT involves engaging the family as a resource to support the individual's recovery. Additionally, evidence-based treatments such as Cognitive-Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and Interpersonal Psychotherapy (IPT) can address psychological and emotional aspects of AN.

Conclusion:
Anorexia Nervosa is a complex and multifaceted eating disorder with significant neurological underpinnings. Its classification as a mental illness helps destigmatize the condition and ensures appropriate treatment for those affected. By employing evidence-based therapies like FBT and addressing the changes in personality and social behavior, we can improve outcomes and support individuals on their journey to recovery.

References:

Treasure, J., Duarte, T. A., & Schmidt, U. (2016). Eating disorders. The Lancet, 387(10027), 1601-1612.

Brooks, S. J., & Stein, D. J. (2016). What's in a name? The nosology of anorexia nervosa. The Lancet Psychiatry, 3(2), 106-107.

Favaro, A., & Santonastaso, P. (2019). Anorexia nervosa: ten-year outcome. Current Psychiatry Reports, 21(12), 124.

Le Grange, D., & Lock, J. (2020). Treatment Manual for Anorexia Nervosa: A Family-Based Approach. Guilford Press. (Book)

Dimitropoulos, G., & Freeman, V. E. (2015). Reward system and feeding behavior in anorexia nervosa: a biomarker of malnutrition severity. Journal of Pediatric Health Care, 29(3), 206-214. (CINAHL)

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