Assignment 5: Process of
immunosuppression
Assignment 5: Process of immunosuppression
A 34-year-old Hispanic-American male with end-stage renal
disease received kidney transplant from a cadaver donor, as no
one in his family was a good match. His post-operative course was
uneventful, and he was discharged with the antirejection drugs
Tacrolimus (Prograf), Cyclosporine (Neoral), and Imuran
(Azathioprine). He did well for 3 months and had returned to his
job as a policeman. Six months after his transplant, he began to
gain weight, had decreased urine output, was very fatigued, and
began to run temperatures up to 101˚F. He was evaluated by his
nephrologist, who diagnosed acute kidney transplant rejection.
Develop a 1- to 2-page case study analysis, examining the patient
symptoms presented in the case study. Be sure to address the
following:
Explain why you think the patient presented the symptoms
described.
The response includes accurate, clear, and detailed reasons, with
explanation for the symptoms supported by evidence and/or
research, as appropriate, to support the explanation.
Identify the genes that may be associated with the development
of the disease.

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