GCU NUR641E Midterm Exam
NUR641E
Advanced Pathophysiology & Pharamacology for Nurse Educators
Midterm
Exam
1 Heparin exerts its therapeutic action
by:
upregulating the activity of one of the
body’s natural anticoagulant molecules, antithrombin III.
deactivating calcium-dependent clotting
factors.
inducing prothrombin formation.
inducing the formation of fibrin.
2 Which method of
drug administration can have immediate effects and requires lower doses
compared to oral or parenteral administration?
Intravenous
Sublingual
Transdermal
Inhalation
3 High altitudes may
produce hypoxemia by:
right-to-left shunts.
atelectasis.
decreased oxygen inspiration.
emphysema.
All of the above
4 Causes of
hyperkalemia include:
hyperparathyroidism and malnutrition.
vomiting and diarrhea.
renal failure and Addison’s disease.
hyperaldosteronism and Cushing’s
disease.
5 Hypomagnesemia
occurs when serum magnesium concentration is less than
1.0 mEq/L.
1.5 mEq/L.
2.0 mEq/L.
3.0 mEq/L.
6 When looking at
arterial blood gas readings, you discover the following: pH 7.26, pCO2 56, HCO3
24. What condition are you dealing with?
Respiratory alkalosis
Metabolic acidosis
Metabolic alkalosis
Respiratory acidosis
7 A drug with a
half-life of 10 hours is administered by continuous intravenous infusion. Which
of the following best approximates the time for the drug to reach steady state?
10 hours
30 hours
40 hours
60 hours
8 Which NSAID is
generally considered the safest for use in patients with coronary artery
disease?
Celecoxib
Indomethacin
Naproxen
Acetaminophen
9 Pulmonary
hypertension:
shows an enlarged pulmonary artery.
involves deep vein thrombosis.
shows right ventricular hypertrophy.
A and C are correct
10 Which stage of
infection is occurring when the immune and inflammatory responses are
triggered?
Incubation period
Prodromal stage
Invasion period
Convalescence
11 Which of the
following agents is used to treat hypercalcemia of malignancy?
Activated vitamin D
Pamidronate (Aredia)
Hydrochlorothiazide
Kayexalate
12 Which statement is
true regarding the pharmacokinetics of drug administration?
The immature liver or kidneys of the
very young may accelerate drug metabolism and excretion.
Medications enter the body in solid
form and change into solution for absorption and utilization.
It includes medication absorption,
distribution to tissues, metabolism, and elimination from the body.
A therapeutic effect occurs as the
medication reaches the target cell.
13 Which statement is
true regarding the half-life of medications?
Doubling the dose will double the medication
half-life.
Approximately 2 half-lives are required
for a medication to be completely eliminated.
Patients with renal or hepatic disease
usually have decreased half-lives.
The half-life of a drug helps determine
how often the drug is to be administered.
