NUR-550 – Translational Research and Population Health Management
Translational Research and Population Health Management Course Syllabus NUR-550
Course Description
In this course, students examine the process of scientific inquiry, knowledge generation, utilization, and dissemination of evidence into advanced nursing practice in order to propose quality improvement initiatives that advance the delivery of safe, high-quality care for patient populations. Students critically evaluate evidence, including scientific findings from the biopsychosocial fields, epidemiology, biostatistics, genetics, and genomics, and apply levels of evidence and theoretical frameworks to design culturally appropriate clinical prevention interventions and population-based care that reduce risks, prevent disease, and promote health and well-being. Students also consider strategies to evaluate health policy and advocacy issues, the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction for diverse populations. Students critically evaluate evidence from the biopsychosocial fields, epidemiology, biostatistics, genetics, and genomics, and apply levels of evidence and theoretical frameworks to design culturally appropriate clinical prevention interventions and population-based care that reduce risks, prevent disease, and promote health and well-being. Students also study methodologies for assessing health policy and advocacy concerns, the state of health care delivery, patient-centered care, and ethical principles pertaining to health beliefs, health promotion, and risk reduction for various groups. Students apply these strategies to work towards recognizing gaps in nursing and health care knowledge, identifying potential solutions or innovations for those gaps, planning and implementing practice changes, and evaluating the outcomes in order to improve practice. Prerequisite: NUR-513.
Topic 1: Quality Research and Theoretical Frameworks
Description
Objectives:
Differentiate translational research from evidencebased
Discuss the application of translational research to population health
Discuss models of translational
Evaluate sources of translational
Study Materials
Advanced Practice Nursing: Essential Knowledge for the Profession
Description:
Read Chapter 22 in Advanced Practice Nursing: Essential Knowledge for the Profession.
Advanced Nursing Research: From Theory to Practice
Description:
Read Chapters 1-3 and 25 in Advanced Nursing Research: From Theory to Practice.
Evidence-Based Practice in Nursing and Healthcare
Description:
Read Chapter 1 in Evidence-Based Practice in Nursing and Healthcare.
Translational Research: A Historical Overview and Contemporary Reflections on the Transformative Nature of Research
Description:
Read “Translational Research: A Historical Overview and Contemporary Reflections on the Transformative Nature of Research,” by Boynton and Elster, from Journal of Research Administration (2012).
Practice-Based Research Priorities for Palliative Care: Results From a Research-to-Practice Consensus Workshop
Description:
Read “Practice-Based Research Priorities for Palliative Care: Results From a Research-to-Practice Consensus Workshop,” by Pillemer, Chen, Riffin, Prigerson, Schultz, and Reid, from American Journal of Public Health (2015). NUR-550 – Translational Research and Population Health Management
Translational Research and Nursing Science
NUR-550 – Translational Research and Population Health Management
Description:
Read “Translational Research and Nursing Science,” by Grady, from Nursing Outlook (2010).
GCU Library: Nursing and Health Sciences Research Guide
Description:
Review the “Nursing and Health Sciences” research guide, located on the GCU Library website.
Translational Research Graphic Organizer Template
Description:
Use the “Translational Research Graphic Organizer Template” to complete the Topic 1 assignment.
Tasks
Evidence-Based Practice Project Proposal: Identification of Nursing Practice Problem
Description:
Learners will select a valid nursing practice problem for an evidence-based practice project proposal. The project will be completed in sections, beginning in NUR-550 and culminating in a final written paper detailing the evidence-based practice proposal in NUR-590.
The purpose of this assignment is to select a relevant nursing practice problem for your evidence-based practice project proposal. To identify a relevant problem, consider problems generally faced in nursing practice (coordination of health care, assessment, education, patient
support, trauma prevention, recovery, health screenings, etc.). Use the “PICOT Draft” template to complete this assignment.
Use a national, state or local population health care database to research indicators of disparity. Choose a mortality/morbidity indicator to identify a clinical problem or issue that you want to explore pertaining to a population of focus. Use this indicator to begin to formulate a PICOT statement.
Refer to the “Evidence-Based Practice Project Proposal – Assignment Overview” document for an overview of the evidence-based practice project proposal assignments.
You are required to cite one peer-reviewed source to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are not required to submit this assignment to LopesWrite.
Topic 1 DQ 1
Description:
Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.
-STUDY NOTES-
Translational research is a process that aims to translate basic scientific discoveries into new treatments, diagnostics, and prevention strategies for patients. It involves a multidisciplinary approach that incorporates findings from basic, preclinical, and clinical research to accelerate the development of new therapies and improve patient care. The different levels of translational research include:
T1 (bench-to-bedside) research: This level of translational research involves the translation of basic laboratory findings into potential treatments or diagnostic tests for patients. This typically involves preclinical research in animal models and early-stage clinical trials in humans.
T2 (bedside-to-population) research: This level of translational research involves the translation of findings from clinical trials into evidence-based practice and population health. This includes the dissemination of new treatments and diagnostic tests to healthcare providers and the development of guidelines for their use in clinical practice.
T3 (population-to-practice) research: This level of translational research involves the translation of findings from population-based studies into community and healthcare systems. This includes the implementation of population health programs, policies and systems that promote the adoption of new therapies and diagnostic tests.
Translational research is different from evidence-based practice in that the latter focuses on using the best available evidence to make clinical decisions, while translational research focuses on applying the scientific knowledge generated from laboratory, preclinical, and clinical studies to improve patient outcomes. Translational research can inform the development of evidence-based guidelines for practice, but also requires the development of new therapies and diagnostic tests as well as the implementation of population health strategies.
Population health management is an approach that seeks to improve the health of a defined population by addressing the multiple determinants of health and promoting evidence-based interventions. Translational research can play a critical role in population health management by providing new treatments and diagnostic tests, evidence-based guidelines and population health strategies that can help reduce the burden of disease and improve health outcomes in a defined population.
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Topic 1 DQ 2
Description:
Using the GCU Library (notably the GCU Library: Nursing and Health Sciences Research Guide), find a database, journal, or other collection of resources that focuses on translational research. Select a population health problem or issue of interest from the available studies. What type of translational research is used for the study? Provide rationale as to why this is the best.
Topic 1 Participation
Description:
NA
Topic 2: Epidemiology, Biostatistics, Genetics, and Genomics
Description
Objectives:
Describe the role of epidemiology in researching population health
Describe the role of epidemiology in addressing population health
Explain the value of biostatistics in population health
Discuss the application of translational research to global
Study Materials
-STUDY NOTES-
The role of epidemiology in researching population health: Epidemiology is the study of the distribution and determinants of health and disease in populations. Epidemiologists use a variety of research methods to study the patterns, causes, and consequences of health and disease in populations. They can use observational studies, such as cross-sectional and cohort studies, as well as experimental studies, such as randomized controlled trials, to investigate the risk factors, outcomes, and potential interventions associated with specific health problems. Epidemiology is critical in researching population health, as it allows scientists to understand the burden of disease in populations, identify the determinants of health and disease and evaluate the effectiveness of interventions.
The role of epidemiology in addressing population health: Epidemiology plays an important role in addressing population health by providing information on the patterns and causes of health and disease in a population. Epidemiological research can identify populations at high risk for specific diseases, and guide the development of evidence-based interventions to reduce that risk. Epidemiology can also identify disparities in health outcomes, and be used to develop targeted interventions to reduce or eliminate these disparities.
The value of biostatistics in population health: Biostatistics is the application of statistical methods to the study of health and disease. Biostatistics is critical in population health research as it allows for the analysis and interpretation of large amounts of data. Biostatisticians work closely with epidemiologists and other public health researchers to design and analyze studies, develop statistical models, and provide guidance on the appropriate use of statistical methods. Biostatistics also helps to establish causal relationships in observational studies, and make inferences about populations using samples of data.
The application of translational research to global health: Translational research can play an important role in improving global health by providing new treatments and diagnostic tests, and developing evidence-based guidelines that can be used to address health problems in low- and middle-income countries. Translational research can also inform the development of population health interventions, and support the implementation of these interventions in resource-limited settings. The application of translational research to global health must take into account the specific needs and constraints of different populations and healthcare systems.
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Advanced Practice Nursing: Essential Knowledge for the Profession
Description:
Read Chapter 19 in Advanced Practice Nursing: Essential Knowledge for the Profession.
Population Health: Creating a Culture of Wellness
Description:
Read Chapters 2 and 3 in Population Health: Creating a Culture of Wellness.
Evidence-Based Practice in Nursing and Healthcare
