Two to three (1-2) slides present a set of critical thinking questions to support the pathophysiology of atrial fibrillation, with thromboemboli formation and subsequent stroke
Atrial fibrillation (AF) is a type of arrhythmia (abnormal heart rhythm) that occurs when the electrical signals that coordinate the contractions of the heart’s atria (the upper chambers) become disorganized and rapid. This can cause the atria to contract in an irregular and inefficient manner, which can lead to a number of complications, including the formation of blood clots.
One of the main complications of AF is the increased risk of thromboemboli formation, which is the formation of blood clots within the heart. These blood clots can then be carried by the bloodstream to other parts of the body, including the brain, where they can cause a stroke.
The pathophysiology of AF-related thromboemboli formation and stroke is complex and involves a number of factors, including:
Abnormal blood flow: The irregular contractions of the atria during AF can cause blood to flow abnormally within the heart, leading to the formation of stagnant pools of blood that can clot.
Reduced cardiac output: AF can also reduce the amount of blood pumped by the heart, which can lead to reduced blood flow to the rest of the body and increase the risk of clot formation.
Inflammation: AF can also cause inflammation within the heart, which can further increase the risk of clot formation.
Risk factors: Other factors that may increase the risk of AF-related thromboemboli formation and stroke include high blood pressure, diabetes, and advanced age.
By understanding the pathophysiology of AF and the factors that contribute to thromboemboli formation and stroke, healthcare professionals can work to prevent and manage these complications in patients with AF.
